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  • Bioestatística com SPSS: notas de apoio
    Publication . Serranho, Pedro; Ramos, Maria do Rosário
    Notas de apoio ao curso de "Biostestatística com SPSS" leccionado pelos Prof. Doutor Francisco Caramelo (Universidade de Coimbra), Prof. Doutora Maria Rosário Ramos e Prof. Doutor Pedro Serranho.
  • Acid phosphatase, some genetic polymorphism and obesity risk factors in adult women
    Publication . Carolino, E.; Oliveira, T.; Silva, A. P.; Carvalho, R; Bicho, M.
    Recent works point out to a relation between some genetic factors and the predisposition for obesity. We believe, therefore, to be relevant to conduct this kind of study in the Portuguese population. In the present work the following genetic factors are considered: Haptoglobin phenotype, the Acid Phosphatasehenotype and two blood group systems, the MN System and the Lewis System. In addition, it was also considered one demographic factor, age, and one enzymatic activity, the Acid Phosphatase Activity. Haptoglobin (Hp) is a hemoglobin-binding protein of the immune system expressed by a genetic polymorphism with three major phenotypes. This protein is associated in some works with susceptibility for common pathological situations, such as some disorders related with obesity. The Acid phosphatase, more precisely the Acid phosphatase locus 1 (ACP1), is a highly polymorphic enzyme that has an important role in flavoenzyme activity and in the control of insulin receptor activity. High ACP1 activity was positively associated with high glycemic levels and with high body mass index (BMI) values. The MN blood system is a blood group system with three phenotypes each one showing different associations with some diseases, including some related with obesity. Finally, the Lewis System was focused on a single locus with two antigens, Le a and Le b. Confirming this characteristic as a genetic marker of obesity may contribute to the explanation of individual differences in the prevalence of obesity. The group under study involves 85 Portuguese adult women with complete data for all variables, taken from a data base with 714 subjects from the Genetic Laboratory, Centre of Endocrinology and Metabolism of University of Lisbon. The aim of the study is to explore and examine the relationship between the weight categories and the explanatory variables, with emphasis on risk for obesity. Therefore, an ordinal regression model was tried, considering as the regressor variables the Haptoglobin phenotype, Acid phosphatase (ACP1) phenotype, MN blood group system, Lewis system, the enzymatic activity of ACP1, age and some association effects between these factors. Some significant main effects were found at a 5% significance level: the phenotypeLe(a-b+) of Lewis System (p-value=0,021) and age (p-value=0,002). The phenotype Le(a-b+) of Lewis System is associated with a decreased risk for obesity (odds ratio 0,139; CI95%(0,016; 0,754)); age (as expected) is associated with an increased risk for obesity (odds ratio 1,11; CI95%(1,038; 1,190))
  • Statistical models for categorical data: brief review for applications in ecology
    Publication . Ramos, Maria do Rosário; Oliveira, Manuela M.; Borges, José G.; McDill, Marc E.
    A brief review of statistical models for prediction of categorical data is presented, with emphasis on the binary type. Several methods have been adopted to build predictive models for binary and other types of categorical data and response variables. The focus here is on generalized linear models and generalized additive models, widely applied in problems in Ecology, when the goal is to fit a model to data of presence/absence type or any other categorical response.The estimation methods used for generalized linear models and generalized additive models as well its statistical properties are discussed. Some examples in ecology are addressed.
  • Environmental Management Systems (EMS) implementation processes and practices in european higher education institutions: top-down versus participatory approaches
    Publication . Disterheft, Antje; Caeiro, Sandra; Ramos, Maria do Rosário; Azeiteiro, Ulisses
    Environmental Management Systems (EMS) have been implemented on a large scale to improve companies’ environmental performance and to certify their achievements. More recently, universities are following this trend, which has been brought forward by the debate about campus sustainability. This empirical international research investigates EMS development and implementation processes in universities around Europe, providing an overview about European higher education institutions with EMS implemented at their campuses, and focuses on a comparison of top-down versus participatory implementation approaches. In addition to regional differences, this article discusses in which aspects an EMS at the campus can be seen as a tool that goes beyond operational aspects to tackle campus sustainability. Furthermore, it provides implications for the professional practice.
  • Assessing the relation between career satisfaction in psychiatry with lifelong learning and scientific activity
    Publication . Afonso, Pedro; Ramos, Maria do Rosário; Saraiva, Sérgio; Moreira, Cátia Alves; Figueira, Maria Luísa
    Lifelong learning (LLL) is an essential feature for the doctor to keep clinically updated and has been described as an indicator of competence and professionalism. The aim of this study was to evaluate the association between career satisfaction in psychiatry, lifelong learning, and commitment in scientific activities, taking into account other personal and professional effects. The survey was sent to 453 national psychiatrists and 190 surveys (41.9%) were completed online and validated. The Jefferson Scale of Physician Lifelong Learning (JSPLL) was used to assess the level of LLL for each doctor. The results of the analysis of JSPLL showed that participants more satisfied with their career have greater motivation and invest more in the LLL. Furthermore, participants who were more satisfied with their career had a higher percentage of scientific activity in the last year. Multiple linear regression with these two effects in the model revealed a positive association between career satisfaction in psychiatry, LLL and the publication of scientific papers, leading to the main conclusion that satisfaction with a career in psychiatry has a significant correlation with LLL and with involvement in scientific activities.
  • Probabilidades e estatística : álgebra dos acontecimentos I
    Publication . Ramos, Maria do Rosário; Barrela, Nuno; Silva, Fátima Ferreira da
    Recurso educativo. Teoria das probabilidades : álgebra dos acontecimentos I
  • Probabilidades e estatística : álgebra dos acontecimentos II
    Publication . Ramos, Maria do Rosário; Barrela, Nuno; Silva, Fátima Ferreira da
    Recurso educativo. Teoria das probabilidades : álgebra dos acontecimentos II
  • Two-way MANCOVA: an application to public health
    Publication . Ramos, Maria do Rosário; Carolino, E.; Oliveira, T.; Bicho, M.
    The aim of this work is to use the MANCOVA model to study the influence of the phenotype of an enzyme – Acid phosphatase – and a genetic factor – Haptoglobin genotype – on two dependent variables - Activity of Acid Phosphatase (ACP1) and the Body Mass Index (BMI). Therefore it's used a general linear model, namely a multivariate analysis of covariance (Two-way MANCOVA). The covariate is the age of the subject. This covariate works as control variable for the independent factors, serving to reduce the error term in the model. The main results showed that only the ACP1 phenotype has a significant effect on the activity of ACP1 and the covariate has a significant effect in both dependent variables. The univariate analysis showed that ACP1 phenotype accounts for about 12.5% of the variability in the activity of ACP1. In respect to this covariate it can be seen that accounts for about 4.6% of the variability in the activity of ACP1 and 37.3% in the BMI.
  • The impact of audit reports on auditor change: verification of the determining factors for auditor change in the portuguese context
    Publication . Heliodoro, Paula; Lopes, Manuel Mouta; Pinho, Carlos; Ramos, Maria do Rosário
    The issue of auditor change and its relation with the opinions issued in financial audit reports is a topic which has been gaining increasing importance in the accounting and auditing areas. The financial audit report represents the final materialization of an external and independent audit. As such, one expects that the opinion expressed by the auditor is not always that forecast by the shareholders or the management of the company being audited. This work attempts to ascertain whether or not a determining relation between a change in auditor and the issuance of qualified audit reports really exists in the Portuguese context, or, on the contrary, if other equally influential factors exist in relation to the said change. The conclusions drawn point to the existence of a significantly positive association between a qualified audit report and a change in auditor, although other relevant factors exist such as the company’s growth rate, governance model and the sector in which it operates
  • Empathy and burnout: a multicentre comparative study between residents and specialists
    Publication . Ferreira, Sara; Afonso, Pedro; Ramos, Maria do Rosário
    Rationale, Aims, and Objectives The prevalence of burnout among medical doctors and its negative effect on empathy can influence therapeutic success. The aim of this study was to compare the levels of empathy and burnout between residents and specialists as well as to study the correlation between empathy and burnout. Methods This is an exploratory study of a convenience sample of 104 doctors who work in health institutions in Greater Lisbon area in Portugal, covering central hospitals, district hospitals, and health centres. Each doctor filled in a questionnaire, which included the Maslach Burnout Inventory (MBI) and the Jefferson Scale of Empathy (JSE). Results Participants were divided in two subgroups: 51% residents (n = 53) and 49% specialists (n = 51). A difference (p = .048) in JSE scores between residents (mean 116.4, SD 12.8) and specialists (mean 120.78, SD 12.84) has been identified. Furthermore, in all three MBI subscales (emotional exhaustion, depersonalization, and lack of personal accomplishment), the group of residents showed significantly higher mean scores. In general, empathy scores showed an inverse relationship between depersonalization (r = –0.390, p < .0001) and lack of personal accomplishment (r = –0.447, p < .0001). Finally, we found that an increase in MBI level is associated with a decrease in empathy levels. Conclusion Our findings suggest that there is a significant difference in burnout subscales scores between residents and specialists and that these have a negative correlation with empathy level. These exploratory results draw attention to the importance of preventing burnout in hospital and health care centres professionals, in particular in residents, through the implementation of individual and organizational structured measures.