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Modeling anesthetic drugs' pharmacodynamic interaction on the bispectral index of the EEG: the influence of heart rate

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dc.contributor.authorNunes, Catarina S.
dc.contributor.authorMendonca, Teresa
dc.contributor.authorBras, Susana
dc.contributor.authorFerreira, David A.
dc.contributor.authorAmorim, Pedro
dc.date.accessioned2023-06-01T08:22:23Z
dc.date.available2023-06-01T08:22:23Z
dc.date.issued2007
dc.description.abstractThe effect of drugs’ interaction on the brain signal Bispectral Index (BIS) is of great importance for an anesthesia control drug infusion system. In this study, the objective was to inspect the influence of patient’s heart rate on the effect of the drugs on BIS. With this goal, the patient’s heart rate was incorporated in an drug interaction model. The model was fitted per patient during anesthesia induction, and tested for prediction under surgery. The results showed that the model with time changing parameters incorporating patient’s heart rate has a better performance than a non adjusted model. Three clusters of models were also identified using the fuzzy cmeans algorithm. These clusters will help to distinguish between different patients’ dynamics.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationC. S. Nunes, T. Mendonca, S. Bras, D. A. Ferreira and P. Amorim, "Modeling Anesthetic Drugs' Pharmacodynamic Interaction on the Bispectral Index of the EEG: the Influence of Heart Rate," 2007 29th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, Lyon, France, 2007, pp. 6479-6482pt_PT
dc.identifier.doi10.1109/IEMBS.2007.4353843pt_PT
dc.identifier.isbn1-4244-0788-5
dc.identifier.pmid18003509
dc.identifier.urihttp://hdl.handle.net/10400.2/13944
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherIEEEpt_PT
dc.titleModeling anesthetic drugs' pharmacodynamic interaction on the bispectral index of the EEG: the influence of heart ratept_PT
dc.typeconference object
dspace.entity.typePublication
oaire.citation.conferencePlaceLyon, Francept_PT
oaire.citation.endPage6482pt_PT
oaire.citation.startPage6479pt_PT
oaire.citation.title29th Annual International Conference of the IEEE Engineering in Medicine and Biology Societypt_PT
person.familyNameDa Costa Nunes Duarte
person.familyNameAmorim
person.givenNameCatarina Sofia
person.givenNamePedro
person.identifier.ciencia-id691F-CDC2-E26A
person.identifier.orcid0000-0002-8357-0994
person.identifier.orcid0000-0001-7466-4174
person.identifier.scopus-author-id55429654100
rcaap.rightsrestrictedAccesspt_PT
rcaap.typeconferenceObjectpt_PT
relation.isAuthorOfPublicationcc3069ec-f930-455f-9226-b77e5d2dc14b
relation.isAuthorOfPublication1ef321dd-4f09-493c-b801-e9a99b28947d
relation.isAuthorOfPublication.latestForDiscoverycc3069ec-f930-455f-9226-b77e5d2dc14b

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