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Biochemical endpoints on juvenile Solea senegalensis exposed

datacite.subject.sdg03:Saúde de Qualidade
dc.contributor.authorCosta, Pedro M.
dc.contributor.authorCaeiro, Sandra
dc.contributor.authorDiniz, Mário S.
dc.contributor.authorLobo, Jorge
dc.contributor.authorMartins, Marta
dc.contributor.authorFerreira, Ana M.
dc.contributor.authorCaetano, Miguel
dc.contributor.authorVale, Carlos
dc.contributor.authorDelValls, T. Ángel
dc.contributor.authorCosta, Maria Helena
dc.date.accessioned2009-10-22T13:25:50Z
dc.date.available2009-10-22T13:25:50Z
dc.date.issued2009
dc.description.abstractJuvenile Solea senegalensis were exposed to fresh sediments from three stations of the Sado estuary (Portugal) in 28-day laboratory assays. Sediments revealed distinct levels of total organic matter, fine fraction, redox potential, trace elements (arsenic, cadmium, chromium, copper, nickel, lead and zinc) and organic contaminants (polycyclic aromatic hydrocarbons, polychlorinated biphenyls and a pesticide: dichloro diphenyl trichloroethane). Organisms were surveyed for contaminant bioaccumulation and induction of two hepatic biochemical biomarkers: metallothionein (MT) and cytochrome P450 (CYP1A), as potential indicators of exposure to metallic and organic contaminants, respectively. Using an integrative approach it was established that, although bioaccumulation is in general accordance with sediment contamination, lethality and biomarker responses are not linearly dependent of the cumulative concentrations of sediment contaminants but rather of their bioavailability and synergistic effects in organisms. It is concluded that metals and organic contaminants modulate both MT and CYP1A induction and it is suggested that reactive oxygen species may be the link between responses and effects of toxicity.pt
dc.description.versionpeerreviewed
dc.identifier.citationCaeiro, Sandra [et al.] - Biochemical endpoints on juvenile Solea senegalensis exposed. "Ecotoxicology" [Em linha]. ISSN 0963-9292 (Print) 1573-3017 (Online). Nº 18 (2009), p. 988–1000pt
dc.identifier.issn0963-9292 (Print)
dc.identifier.issn1573-3017 (Online)
dc.identifier.urihttp://hdl.handle.net/10400.2/1399
dc.language.isoengpt
dc.publisherSpringer
dc.relation.publisherversionDOI 10.1007/s10646-009-0373-7
dc.subjectSenegalese solept
dc.subjectContaminated sedimentspt
dc.subjectBioaccumulationpt
dc.subjectMetallothioneinpt
dc.subjectCYP1Apt
dc.subjectSado estuarypt
dc.titleBiochemical endpoints on juvenile Solea senegalensis exposedpt
dc.typejournal article
dspace.entity.typePublication
person.familyNameCaeiro
person.familyNameCaetano
person.givenNameSandra
person.givenNameMiguel
person.identifier587808
person.identifier507243
person.identifier.ciencia-id8515-398A-D241
person.identifier.ciencia-id4F1D-56C9-BBFB
person.identifier.orcid 0000-0002-6079-3554
person.identifier.orcid0000-0001-5121-0719
person.identifier.ridK-3886-2014
person.identifier.scopus-author-id6603297853
person.identifier.scopus-author-id7003777195
rcaap.rightsopenAccesspt
rcaap.typearticlept
relation.isAuthorOfPublicatione2a8250a-8f09-4f11-a04e-1a3056644ff3
relation.isAuthorOfPublication8cf16fd9-7d07-4a51-abba-deca3df2aed2
relation.isAuthorOfPublication.latestForDiscovery8cf16fd9-7d07-4a51-abba-deca3df2aed2

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