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May sediment contamination be xenoestrogenic to benthic fish? : a case study with Solea senegalensis

datacite.subject.sdg03:Saúde de Qualidade
datacite.subject.sdg14:Proteger a Vida Marinha
dc.contributor.authorGonçalves, Cátia
dc.contributor.authorMartins, Marta
dc.contributor.authorDiniz, Mário
dc.contributor.authorCosta, Maria Helena
dc.contributor.authorCaeiro, Sandra
dc.contributor.authorCosta, Pedro M.
dc.date.accessioned2015-02-27T16:53:29Z
dc.date.available2015-09-01T00:30:05Z
dc.date.issued2014-05
dc.description.abstractWithin an environmental risk assessment framework of a moderately contaminated estuary (the Sado, SW Portugal), the present work intended to detect endocrine disruption in a flatfish, Solea senegalensis Kaup, 1858, and its potential relationship to organic toxicants. Animals were collected from two distinct areas in the estuary (industrial and rural) and from an external reference area. Hepatic vitellogenin (VTG) levels, cytochrome P450 (CYP1A) induction, ethoxyresorufin-O-deethylase (EROD) activity plus gonad histology were analysed. Males and females were sexually immature and showed no significant evidence of degenerative pathologies. However, hepatic VTG concentrations in males from the industrial area were higher than Reference, even reaching levels comparable to females, indicating low but measurable oestrogenic effects caused by the complex contaminant mixture in estuarine sediments. These in- dividuals also presented elevated CYP1A induction and EROD activity, which is consistent with contamination by organic toxicants such as PAHs and other aryl hydrocarbon receptor (Ahr) -mediated toxicants.por
dc.identifier.doihttp://dx.doi.org/10.1016/j.marenvres.2014.04.012
dc.identifier.issn0141-1136
dc.identifier.issn1879-0291
dc.identifier.urihttp://hdl.handle.net/10400.2/3732
dc.language.isoengpor
dc.peerreviewedyespor
dc.publisherElsevierpor
dc.subjectFlatfishpor
dc.subjectEDCspor
dc.subjectPollution monitoringpor
dc.subjectMixturespor
dc.subjectVitellogeninpor
dc.subjectCYP1Apor
dc.subjectERODpor
dc.titleMay sediment contamination be xenoestrogenic to benthic fish? : a case study with Solea senegalensispor
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage178por
oaire.citation.startPage170por
oaire.citation.titleMarine Environmental Researchpor
oaire.citation.volume99por
person.familyNameCaeiro
person.givenNameSandra
person.identifier587808
person.identifier.ciencia-id8515-398A-D241
person.identifier.orcid 0000-0002-6079-3554
person.identifier.ridK-3886-2014
person.identifier.scopus-author-id6603297853
rcaap.rightsrestrictedAccesspor
rcaap.typearticlepor
relation.isAuthorOfPublicatione2a8250a-8f09-4f11-a04e-1a3056644ff3
relation.isAuthorOfPublication.latestForDiscoverye2a8250a-8f09-4f11-a04e-1a3056644ff3

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