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Multivariable fuzzy control for the simultaneous administration of the anaesthetic and the analgesic drugs

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dc.contributor.authorNunes, Catarina S.
dc.contributor.authorMahfouf, M.
dc.contributor.authorLinkens, D. A.
dc.contributor.authorPeacock, J.
dc.date.accessioned2023-05-31T15:14:56Z
dc.date.available2023-05-31T15:14:56Z
dc.date.issued2003
dc.description.abstractA multivariable fuzzy controller developed for the simultaneous administration of the anaesthetic drug (propofol) and the analgesic drug (remifentanil), is presented. The controller was designed in order to achieve a steady state level of depth of anaesthesia (DOA) and to reduce the amount of drug infused. The multivariable fuzzy controller is based on linguistic rules that interact with three decision tables, one of which represents a fuzzy PI controller. Optimisation using genetic algorithms was used to determine the scaling factors of the fuzzy PI controller. According to the different possibilities for the DOA level and for the surgical stimuli, the multivariable controller defines the required change in the infusion rates of the two drugs. A patient model of the interaction between propofol and remifentanil was used to test the multivariable controller. The controller was able to adjust the remifentanil infusion rate according to the stimulus intensity, and takes advantage of the synergistic interaction to the change adequately the propofol infusion rate. Propofol is titrated to lower infusion rates, decreasing the amount of drug infused, and speeding up recovery. In addition, the controller ensures adequate analgesia by titrating the remifentanil according to stimulus. The multivariable fuzzy controller was tested under different simulations, and responded efficiently to different induction profiles, set point changes and disturbances.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationC. S. Nunes, M. Mahfouf, D. A. Linkens and J. Peacock, "Multivariable fuzzy control for the simultaneous administration of the anaesthetic and the analgesic drugs," 2003 European Control Conference (ECC), Cambridge, UK, 2003, pp. 1046-1051pt_PT
dc.identifier.doi10.23919/ECC.2003.7085097pt_PT
dc.identifier.isbn978-3-9524173-7-9
dc.identifier.urihttp://hdl.handle.net/10400.2/13941
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherIEEEpt_PT
dc.subjectMultivariable controlpt_PT
dc.subjectFuzzy logicpt_PT
dc.subjectDepth of anaesthesiapt_PT
dc.subjectAnalgesiapt_PT
dc.subjectSynergistic interactionspt_PT
dc.titleMultivariable fuzzy control for the simultaneous administration of the anaesthetic and the analgesic drugspt_PT
dc.typeconference object
dspace.entity.typePublication
oaire.citation.conferencePlaceCambridge, UKpt_PT
oaire.citation.endPage1051pt_PT
oaire.citation.startPage1046pt_PT
oaire.citation.titleEuropean Control Conference (ECC)pt_PT
person.familyNameNunes
person.givenNameCatarina S.
person.identifier.ciencia-id691F-CDC2-E26A
person.identifier.orcid0000-0002-8357-0994
rcaap.rightsrestrictedAccesspt_PT
rcaap.typeconferenceObjectpt_PT
relation.isAuthorOfPublicationcc3069ec-f930-455f-9226-b77e5d2dc14b
relation.isAuthorOfPublication.latestForDiscoverycc3069ec-f930-455f-9226-b77e5d2dc14b

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