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Publicação
Brain monitoring in dogs using the cerebral state index during the induction of anaesthesia via target-controlled infusion of propofol
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Orientador(es)
Resumo(s)
The aim of this study was to evaluate the correlation between the cerebral state index (CSI) and the estimated propofol plasma concentrations in dogs during induction of anaesthesia.
Fifteen healthy dogs undergoing scheduled routine surgical procedures were enrolled in this study. Target controlled infusion (TCI)
software, based on the pharmacokinetic model for propofol, was used to control the syringe pump and to estimate plasma propofol concentrations (PropCp) and the CSI values every five-seconds. Three electrodes placed in the centre of the forehead, on the left side of the
forehead and on the left mastoid were used to collect the electroencephalographic (EEG) signal converted by the cerebral state monitor
into the CSI.
The cerebral electrical changes induced by increasing propofol concentrations appear to be detected by CSI monitoring in dogs. The
negative correlation between CSI and PropCp demonstrates that the CSI could be used to assess electrical brain activity in dogs during
the induction of anaesthesia with propofol.
Descrição
Palavras-chave
CSI Cerebral state index TCI Propofol Brain monitoring
Contexto Educativo
Citação
Ribeiro, L.M., D. A. Ferreira, N. M. Bressan, C.S. Nunes, P. Amorim, and L. M. Antunes (2008) "Brain monitoring in dogs using the cerebral state index during the induction of anaesthesia via target-controlled infusion of propofol," Research in Veterinary Science, 85(2): 227-232.
Editora
Elsevier