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Control of depth of anesthesia using MUSMAR: exploring electromyography and the analgesic dose as accessible disturbances

dc.contributor.authorNunes, Catarina S.
dc.contributor.authorMendonca, Teresa
dc.contributor.authorLemos, Joao M.
dc.contributor.authorAmorim, Pedro
dc.date.accessioned2023-06-01T08:15:47Z
dc.date.available2023-06-01T08:15:47Z
dc.date.issued2007
dc.description.abstractThe problem of controlling the level of depth of anesthesia measured by the Bispectral Index (BIS) of the electroencephalogram of patients under general anesthesia, is considered. It is assumed that the manipulated variable is the infusion rate of the hypnotic drug propofol, while the drug remifentanil is also administered for analgesia. Since these two drugs interact, the administration rate of remifentanil is considered as an accessible disturbance in combination with the level of electromyography (EMG) that also interferes with the BIS signal. In order to tackle the high uncertainty present on the system, the predictive adaptive controller MUSMAR is used. The performance of the controller is illustrated by means of simulation with 45 patient individual adjusted models, which incorporate the effect of the drugs interaction on BIS. This controller structure proved to be robust to the EMG and remifentanil disturbances, patient variability, changing reference values and noise.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.doi10.1109/IEMBS.2007.4352605pt_PT
dc.identifier.isbn1-4244-0788-5
dc.identifier.pmid18002271
dc.identifier.urihttp://hdl.handle.net/10400.2/13943
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherIEEEpt_PT
dc.titleControl of depth of anesthesia using MUSMAR: exploring electromyography and the analgesic dose as accessible disturbancespt_PT
dc.typeconference object
dspace.entity.typePublication
oaire.citation.conferencePlaceLyon, Francept_PT
oaire.citation.endPage1577pt_PT
oaire.citation.startPage1574pt_PT
oaire.citation.title29th Annual International Conference of the IEEE Engineering in Medicine and Biology Societypt_PT
person.familyNameDa Costa Nunes Duarte
person.familyNameAmorim
person.givenNameCatarina Sofia
person.givenNamePedro
person.identifier.ciencia-id691F-CDC2-E26A
person.identifier.orcid0000-0002-8357-0994
person.identifier.orcid0000-0001-7466-4174
person.identifier.scopus-author-id55429654100
rcaap.rightsrestrictedAccesspt_PT
rcaap.typeconferenceObjectpt_PT
relation.isAuthorOfPublicationcc3069ec-f930-455f-9226-b77e5d2dc14b
relation.isAuthorOfPublication1ef321dd-4f09-493c-b801-e9a99b28947d
relation.isAuthorOfPublication.latestForDiscoverycc3069ec-f930-455f-9226-b77e5d2dc14b

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