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Advisor(s)
Abstract(s)
The effect of drugs’ interaction on the hemodynamic variables is of great importance when considering
patient’s safety and stability. It is also important for control
infusion systems during anesthesia. In this article, an adaptivenetwork fuzzy inference system is used to model the effect of two
drugs (propofol and remifentanil) on the mean arterial pressure
and heart rate. The clinical data of 45 patients is used to train
and test the model. The use of subtractive clustering improved
the model performance on the testing data set. The fuzzy model
is able to capture the synergistic interaction between the two
drugs, but other influences were detected.
Description
Keywords
Citation
C. S. Nunes and P. Amorim, "A neuro-fuzzy approach for predicting hemodynamic responses during anesthesia," 2008 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, Vancouver, BC, Canada, 2008, pp. 5814-5817