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Two-way MANCOVA: an application to public health

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datacite.subject.sdg03:Saúde de Qualidadept_PT
dc.contributor.authorRamos, Maria do Rosário
dc.contributor.authorCarolino, E.
dc.contributor.authorOliveira, T.
dc.contributor.authorBicho, M.
dc.date.accessioned2023-08-02T14:29:55Z
dc.date.available2023-08-02T14:29:55Z
dc.date.issued2012
dc.description.abstractThe aim of this work is to use the MANCOVA model to study the influence of the phenotype of an enzyme – Acid phosphatase – and a genetic factor – Haptoglobin genotype – on two dependent variables - Activity of Acid Phosphatase (ACP1) and the Body Mass Index (BMI). Therefore it's used a general linear model, namely a multivariate analysis of covariance (Two-way MANCOVA). The covariate is the age of the subject. This covariate works as control variable for the independent factors, serving to reduce the error term in the model. The main results showed that only the ACP1 phenotype has a significant effect on the activity of ACP1 and the covariate has a significant effect in both dependent variables. The univariate analysis showed that ACP1 phenotype accounts for about 12.5% of the variability in the activity of ACP1. In respect to this covariate it can be seen that accounts for about 4.6% of the variability in the activity of ACP1 and 37.3% in the BMI.pt_PT
dc.description.sponsorshipThe authors would like to thank Professor Tadeuz Caliski for the valuable comments to the first version of the work contributing to its improvement and to A. P. Silva, R. Carvalho from Genetics Laboratory, FML-University of Lisbon, for making available the data set for this study and clarification on its characteristics. This research was partially sponsored by Fundação para a Ciência e Tecnologia (FCT) under the projects PEst-OE/MAT/UI0006/2011 and PEst-OE/MAT/UI0209/2011
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationRamos, M. R., Carolino, E., Oliveira, T., & Bicho, M. (2012). Two-way MANCOVA: An application to public health. AIP Conference Proceedings.1479, 1716. https://doi.org/10.1063/1.4756503pt_PT
dc.identifier.doi10.1063/1.4756503pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.2/14719
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherAIP Publishingpt_PT
dc.subjectAcid phosphatase (ACP1)pt_PT
dc.subjectBody mass indexpt_PT
dc.subjectHaptoglobinpt_PT
dc.subjectMANCOVApt_PT
dc.subjectGLMpt_PT
dc.titleTwo-way MANCOVA: an application to public healthpt_PT
dc.typeconference object
dspace.entity.typePublication
oaire.citation.conferencePlaceKos, Greecept_PT
oaire.citation.endPage1719pt_PT
oaire.citation.startPage1716pt_PT
oaire.citation.titleICNAAM 2012. AIP Conference Proceedings, International Conference of Numerical Analysis and Applied Mathematicspt_PT
person.familyNameRamos
person.givenNameMaria do Rosário
person.identifier206757
person.identifier.ciencia-id3A1F-E648-078D
person.identifier.orcid0000-0001-9114-0807
person.identifier.ridP-4530-2015
person.identifier.scopus-author-id54403639500
rcaap.rightsrestrictedAccesspt_PT
rcaap.typeconferenceObjectpt_PT
relation.isAuthorOfPublicationc6cdb7b7-607d-4775-947f-d153ff6dded2
relation.isAuthorOfPublication.latestForDiscoveryc6cdb7b7-607d-4775-947f-d153ff6dded2

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