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Usefulness of the blink reflex to assess the effect of propofol during induction of anesthesia in surgical patients

dc.contributor.authorFerreira, Ana Isabel Leitão
dc.contributor.authorNunes, Catarina S.
dc.contributor.authorMendes, Joaquim
dc.contributor.authorAmorim, Pedro
dc.date.accessioned2021-11-24T12:43:53Z
dc.date.available2021-11-24T12:43:53Z
dc.date.issued2020
dc.descriptionMEDICON 2019 : XV Conferência Mediterrânea sobre Engenharia Médica e Biológica e Computaçãopt_PT
dc.description.abstractThe aim of this study was to investigate the relation between the blink reflex evoked by an electrical stimulus and the depth of anesthesia induced with intravenous anesthetic drug propofol. The blink reflex was stimulated before the propofol infusion started (baseline) and after, every 6 s. The electromyographic responses and the level of sedation/anesthesia scores as well as the estimated effect-site concentration of propofol were recorded in 11 patients. The blink reflex responses were abolished when patients were still conscious. The clinical scale of anesthesia increased with increasing concentrations of propofol. To predict the level of sedation/anesthesia a multinomial logistic regression was performed using blink reflex extracted features at the frequency domain. Several features proved to be good predictor estimates and the model showed to be useful. This information could be helpful to assess the moment of loss of consciousness and thus personalize anesthesia.pt_PT
dc.description.abstractO objetivo deste estudo foi investigar a relação entre o reflexo de piscar evocado por um estímulo elétrico e a profundidade da anestesia induzida com o anestésico propofol intravenoso. O reflexo de piscar foi estimulado antes do início da infusão de propofol (linha de base) e após, a cada 6 s. As respostas eletromiográficas e os escores de nível de sedação / anestesia, bem como a concentração estimada de propofol no local do efeito, foram registrados em 11 pacientes. As respostas do reflexo de piscar foram abolidas quando os pacientes ainda estavam conscientes. A escala clínica da anestesia aumentou com o aumento das concentrações de propofol. Para prever o nível de sedação / anestesia, uma regressão logística multinomial foi realizada usando recursos extraídos do reflexo de piscar no domínio da frequência. Vários recursos provaram ser boas estimativas de preditor e o modelo mostrou-se útil. Essas informações podem ser úteis para avaliar o momento de perda de consciência e, assim, personalizar a anestesia.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationFerreira A.L., Nunes C.S., Mendes J.G., Amorim P. (2020) Usefulness of the Blink Reflex to Assess the Effect of Propofol During Induction of Anesthesia in Surgical Patients. In: Henriques J., Neves N., de Carvalho P. (eds) XV Mediterranean Conference on Medical and Biological Engineering and Computing – MEDICON 2019. MEDICON 2019. IFMBE Proceedings, vol 76 (pp. 1057-1063). Springer, Champt_PT
dc.identifier.doi10.1007/978-3-030-31635-8_128pt_PT
dc.identifier.isbn978-3-030-31634-1 (Print)
dc.identifier.isbn978-3-030-31635-8 (Online)
dc.identifier.urihttp://hdl.handle.net/10400.2/11414
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherSpringer Naturept_PT
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/4.0/pt_PT
dc.subjectPropofolpt_PT
dc.subjectAnesthesiapt_PT
dc.subjectLoss of consciousnesspt_PT
dc.subjectBlink reflexpt_PT
dc.subjectElectromyographypt_PT
dc.subjectMultinomial logistic regressionpt_PT
dc.subjectFrequency analysispt_PT
dc.subjectAnestesiapt_PT
dc.subjectPerda de consciênciapt_PT
dc.subjectReflexo de piscarpt_PT
dc.subjectEletromiografiapt_PT
dc.subjectRegressão logística multinomialpt_PT
dc.subjectAnálise de frequênciapt_PT
dc.titleUsefulness of the blink reflex to assess the effect of propofol during induction of anesthesia in surgical patientspt_PT
dc.title.alternativeUtilidade do reflexo intermitente para avaliar o efeito do propofol durante a indução da anestesia em pacientes cirúrgicospt_PT
dc.typeconference object
dspace.entity.typePublication
oaire.citation.endPage1063pt_PT
oaire.citation.startPage1057pt_PT
oaire.citation.titleIFMBE Proceedingspt_PT
oaire.citation.volume76pt_PT
person.familyNameFerreira
person.familyNameNunes
person.familyNameMendes
person.familyNameAmorim
person.givenNameAna
person.givenNameCatarina S.
person.givenNameJoaquim
person.givenNamePedro
person.identifierR-000-7HY
person.identifier.ciencia-id791E-88E5-5BD7
person.identifier.ciencia-id691F-CDC2-E26A
person.identifier.ciencia-id301B-ED0C-A4FE
person.identifier.orcid0000-0003-2350-6947
person.identifier.orcid0000-0002-8357-0994
person.identifier.orcid0000-0003-4254-1879
person.identifier.orcid0000-0001-7466-4174
person.identifier.ridH-8140-2014
person.identifier.ridO-5655-2016
person.identifier.scopus-author-id57204246003
person.identifier.scopus-author-id35931916900
person.identifier.scopus-author-id55429654100
rcaap.rightsrestrictedAccesspt_PT
rcaap.typeconferenceObjectpt_PT
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