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Publication
Deceased-donor kidney transplantation: predictive factors and impact on postoperative outcome
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Advisor(s)
Abstract(s)
Kidney transplantation (KT) is the treatment of choice in end stage renal disease. Patients proposed for KT have multiple comorbidities, which makes KT a challenge. Our aim was to assess predictive factors for postoperative complications in deceased-donor KT. For data statistical analysis, logistic and linear regressions were used. Between 2012 and 2013, 113 KTs were performed in patients with a mean age 49.9 years. The most prevalent etiology was unknown (32.7%). All patients were in kidney replacement therapy (KRT), for an average of 5.7 years. Most had comorbidities before KT (84.1%), the most frequent hypertension (82.3%). Mean ischemia time (IT) was 1056 minutes. Complications occurred in 93.8% of cases. There were reinterventions in 12.4% of cases, and reinterventions in 13.3%. The time in KRT, IT, and ischemic heart disease had predictive power for the length of hospital stay. Diabetes mellitus before KT and IT were predictors for nephrourologic complications; anemia before KT for hematologic complications; and anemia before KT and time in KRT for cardiovascular complications. The morbidity associated with this disease points to the need to identify and improve the patient-dependent variables influencing its outcome, so as to improve short-term success.
Description
Keywords
Adult Cadaver Cold ischemia Comorbidity Female Humans Kidney failure, Chronic Kidney transplantation Length of stay Male Middle aged Postoperative complications Renal dialysis Retrospective studies Warm ischemia
Pedagogical Context
Citation
Araujo AM, Santos F, Guimaraes J, Nunes CS, Casal M (2015). "Living-donor Kidney Transplantation: Predictive Factors and Impact on Post-transplant Outcome." Transplantation Proceedings 47(4): 938-941
Publisher
Elsevier