Matemática e Estatística | Comunicações em congressos, conferências e seminários / Communications in congresses, conferences
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- Controlling the hypnotic drug (propofol) to maintain a stable depth of anesthesia, in dogsPublication . Bras, Susana; Ribeiro, Lenio; Ferreira, David A.; Antunes, Luis; Nunes, Catarina S.The development of control and automatic systems is important to guarantee a stable anesthesia, with no under or over dosage, and no awareness episodes. In this study a controller for the Cerebral State Index (CSI — an electroencephalogram derived signal) was developed. This study was a simulation study, the CSI was modeled using a fuzzy logic model with two inputs the effect-site concentration of propofol and the electromyography (EMG). The controller was tested using constant and variable references in an exhaustive set of simulations. The controller developed presents a good performance in all simulations and the controlled variable seems to be influenced by electromyography level. A controller for propofol anesthesia for veterinary use is an important step towards the improvement of animal welfare. The overall aim is to improve animal safety and comfort.
- Nonlinear modeling of cerebral state index in dogsPublication . Bras, Susana; Bressan, Nadja; Ribeiro, Lenio; Ferreira, David A.; Antunes, Luis; Nunes, Catarina S.The Cerebral State Index (CSI) is an electroencephalogram derived signal representing the depression of central nervous activity produced by anesthetic drugs. In this study, a nonlinear model was developed to describe the CSI tendency during general anesthesia in dogs, by evaluating the effect of the anesthetic drug propofol. The model was based on a compartmental and Hill Equation structure with individually identified parameters. The clinical data of 14 dog surgeries were collected and used for modeling and testing. The model presented good results, following the CSI trend. A model for drug-effect for veterinarian anesthesia is an important step when developing advisory, educational and control systems. The overall aim is to improve animal safety and comfort.