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Performance of blink reflex in patients during anesthesia induction with propofol and remifentanil: prediction probabilities and multinomial logistic analysis

2020-11-14Journal article Open access
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dc.contributor.authorFerreira, Ana Isabel Leitão
dc.contributor.authorVide, Sérgio
dc.contributor.authorFelgueiras, João
dc.contributor.authorCardoso, Márcio
dc.contributor.authorAmorim, Pedro
dc.contributor.authorMendes, Joaquim
dc.contributor.authorNunes, Catarina S.
dc.date.accessioned2021-01-18T13:43:14Z
dc.date.available2021-01-18T13:43:14Z
dc.date.issued2020-11-14
dc.description.abstractThe amount of propofol needed to induce loss of responsiveness varied widely among patients, and they usually required less than the initial dose recommended by the drug package inserts. Identifying precisely the moment of loss of responsiveness will determine the amount of propofol each patient needs. Currently, methods to decide the exact moment of loss of responsiveness are based on subjective analysis, and the monitors that use objective methods fail in precision. Based on previous studies, we believe that the blink reflex can be useful to characterize, more objectively, the transition from responsiveness to unresponsiveness. The purpose of this study is to investigate the relation between the electrically evoked blink reflex and the level of sedation/anesthesia measured with an adapted version of the Richmond Agitation-Sedation Scale, during the induction phase of general anesthesia with propofol and remifentanil. Adding the blink reflex to other variables may allow a more objective assessment of the exact moment of loss of responsiveness and a more personalized approach to anesthesia induction.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationFerreira, A.L., Nunes, C.S., Vide, S. et al. Performance of blink reflex in patients during anesthesia induction with propofol and remifentanil: prediction probabilities and multinomial logistic analysis. BioMed Eng OnLine 19, 84 (2020). https://doi.org/10.1186/s12938-020-00828-6pt_PT
dc.identifier.doi10.1186/s12938-020-00828-6pt_PT
dc.identifier.issn1475-925X
dc.identifier.urihttp://hdl.handle.net/10400.2/10414
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherSpringer Naturept_PT
dc.relationAdvanced Consciousness Assessment for Anaesthesia
dc.relation.publisherversionhttps://biomedical-engineering-online.biomedcentral.com/articles/10.1186/s12938-020-00828-6pt_PT
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.subjectPredictionpt_PT
dc.subjectBlink reflexpt_PT
dc.subjectLoss of responsivenesspt_PT
dc.titlePerformance of blink reflex in patients during anesthesia induction with propofol and remifentanil: prediction probabilities and multinomial logistic analysispt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.awardTitleAdvanced Consciousness Assessment for Anaesthesia
oaire.awardURIinfo:eu-repo/grantAgreement/FCT//SFRH%2FBD%2F98915%2F2013/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/5876/UID%2FEMS%2F50022%2F2013/PT
oaire.citation.startPage84pt_PT
oaire.citation.titleBioMedical Engineering OnLinept_PT
oaire.fundingStream5876
person.familyNameFerreira
person.familyNameVide
person.familyNameAmorim
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person.familyNameNunes
person.givenNameAna
person.givenNameSérgio
person.givenNamePedro
person.givenNameJoaquim
person.givenNameCatarina S.
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person.identifier.orcid0000-0002-8357-0994
person.identifier.ridH-8140-2014
person.identifier.ridO-5655-2016
person.identifier.scopus-author-id57204246003
person.identifier.scopus-author-id55429654100
person.identifier.scopus-author-id35931916900
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
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