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Hydroxyethyl starch 130/0.4 can be useful to prevent a hemodynamic response to a single dose of remifentanil
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Advisor(s)
Abstract(s)
El propofol y el remifentanilo se utilizan frecuentemente para la anestesia intravenosa. El uso combinado
de las dos drogas tiende a causar depresión hemodinámica. Describimos, en dos pacientes, la ausencia de efectos hemodinámicos en respuesta a la administración de
propofol y remifentanilo al combinarlo con la infusión
de hidroxietilalmidón (HES) 130/0,4. Durante la inducción de la anestesia y debido a la necesidad de reponer el
volumen sanguíneo, dos pacientes de 62 y 65 años recibieron una solución intravenosa de HES 130/0,4. A continuación, les fue administrado un bolus de 2 µg Kg–1 de
remifentanilo bajo anestesia intravenosa total (TIVA)
con propofol y remifentanilo, antes de la colocación del
cabezal de Mayfield®. No observamos cambios en la presión arterial media ni en la frecuencia cardiaca como
respuesta al bolus de remifentanilo en los pacientes que
recibieron HES 130/0,4 bajo TIVA con propofol y remifentanilo. El HES 130/0,4 puede tener un papel activo en
la prevención de la respuesta hemodinámica al remifentanilo al combinarlo con propofol. Para confirmar estos
resultados es necesario realizar un estudio randomizado.
Intravenous propofol and remifentanil are often used in anesthesia. The combined use of these drugs tends to cause hemodynamic depression. We describe the absence of hemodynamic effects in response to infusion of propofol and remifentanil when hydroxyethyl starch (HES) 130/0.4 was also administered. During induction, because blood volume needed to be replaced, two patients aged 62 and 65 years received intravenous HES 130/0.4. They then received a single dose of 2 µg·kg-1 of remifentanil during total intravenous anesthesia (TIVA) with propofol and remifentanil before placement of a Mayfield® head holder. No changes in mean blood pressure or heart rate were observed in either patient after the remifentanil bolus when they have received HES 130/0.4 during TIVA with propofol and remifentanil HES 130/0.4 may play an active role in preventing a hemodynamic response to remifentanil bolus. This hypothesis should be tested in a randomized controlled trial.
Intravenous propofol and remifentanil are often used in anesthesia. The combined use of these drugs tends to cause hemodynamic depression. We describe the absence of hemodynamic effects in response to infusion of propofol and remifentanil when hydroxyethyl starch (HES) 130/0.4 was also administered. During induction, because blood volume needed to be replaced, two patients aged 62 and 65 years received intravenous HES 130/0.4. They then received a single dose of 2 µg·kg-1 of remifentanil during total intravenous anesthesia (TIVA) with propofol and remifentanil before placement of a Mayfield® head holder. No changes in mean blood pressure or heart rate were observed in either patient after the remifentanil bolus when they have received HES 130/0.4 during TIVA with propofol and remifentanil HES 130/0.4 may play an active role in preventing a hemodynamic response to remifentanil bolus. This hypothesis should be tested in a randomized controlled trial.
Description
Keywords
Remifentanilo HES 130-0,4 Frecuencia cardiaca Presión sanguínea Remifentanil HES 130/0.4 Heart rate Blood pressure
Citation
Ferreira, D., I. Santos, C.S. Nunes, P. Amorim, and L. Antunes (2005) "El hidroxietilalmidón (HES) 130/0,4 puede ser útil en la Prevención de la Respuesta Hemodinámica a un Bolus de Remifentanilo," Revista Espanola de Anestesiologia y Reanimacion, 52(9): 550-553.
Publisher
Elsevier