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Browsing by Author "Moreira, A. Paulo"

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  • Anaesthesia synchronization software: target controlled infusion system evaluation
    Publication . Bressan, Nadja; Moreira, A. Paulo; Amorim, Pedro; Nunes, Catarina S.
    Target Controlled Infusion (TCI) systems are based in drug Pharmacokinetic (Pk) and Pharmacodynamic (Pd) models implemented in an algorithm to drive an infusion device. Several studies had compare manual titration of anesthesia and TCI system use; some studies evaluate the performance of the control algorithms for TCI systems, and a considerable number of studies assess the performance of Pk/Pd models implemented into TCI systems. This study presents a set of tests to validate the performance of a TCI system as a computer-aided. The goal of the current study was to assess the performance of the TCI system, Anaesthesia Synchronization Software (ASYS), on clinical set up to evaluate communication consistence (computer - infusion device) and controller performance in real time. These measures provided quantitative and qualitative evidences of software robustness and accuracy to be used at clinical environment.
    2010Conference object Restricted access Show more
  • Target controlled infusion algorithms for anesthesia: Theory vs practical implementation
    Publication . Bressan, Nadja; Moreira, A. Paulo; Amorim, Pedro; Nunes, Catarina S.
    Target Controlled Infusion (TCI) systems are based in drug pharmacokinetic and pharmacodynamic models implemented in an algorithm to drive an infusion pump. Infusion control algorithms have been designed, implemented and validated for several anesthetic drugs, devices and controllers. The maintenance phase in these algorithms is represented by an equation that compensates the loss of drug from the central compartment and maintains the set target concentration. The goal of the current study was to improve existing TCI software with a new method for the maintenance phase. We compared and analyzed two different methods to find the more efficient method for the maintenance phase in an open-loop control TCI system.
    2009Conference object Restricted access Show more