Guimarães, PedroRodrigues, PedroCelorico, DirceSerranho, PedroBernardes, Rui2015-04-302015-04-302015Guimarães, Pedro [et al.] - Three-dimensional segmentation and reconstruction of the retinal vasculature from spectral-domain optical coherence tomography. "Journal of Biomedical Optics" [Em linha]. ISSN 1083-3668 (Print) 1560-228 (Online). Vol. 20, nº 1 (jan. 2015), 20 p.1083-36681560-2281http://hdl.handle.net/10400.2/3907In this work we reconstruct the 3-D shape and location of the retinal vascular network from commercial spectral-domain (SD) optical coherence tomography (OCT) data. The 2-D location of retinal vascular network on the eye fundus is obtained through SVM classification of properly defined fundus images from OCT data,1 taking advantage of the fact that on standard SD-OCT the incident light beam is absorbed by haemoglobin, therefore creating a shadow cast on OCT signal below each perfused vessel. The depth-wise location of the vessel is obtained as the beginning of the shadow. The classification of crossovers and bifurcations within the vascular network is also addressed. We illustrate the feasibility of the method in terms of vessel calibre estimation and the accuracy of bifurcations and crossovers classification.porOptical coherence tomographyVascular systemRetinajournal article2015-02-2710.1117/1.JBO.20.1.016006