Utilize este identificador para referenciar este registo:
|Título:||Biochemical endpoints on juvenile Solea senegalensis exposed|
|Autor:||Costa, Pedro M.|
Diniz, Mário S.
Ferreira, Ana M.
Costa, Maria Helena
|Citação:||Caeiro, Sandra [et al.] - Biochemical endpoints on juvenile Solea senegalensis exposed. "Ecotoxicology" [Em linha]. ISSN 0963-9292 (Print) 1573-3017 (Online). Nº 18 (2009), p. 988–1000|
|Resumo:||Juvenile Solea senegalensis were exposed to fresh sediments from three stations of the Sado estuary (Portugal) in 28-day laboratory assays. Sediments revealed distinct levels of total organic matter, fine fraction, redox potential, trace elements (arsenic, cadmium, chromium, copper, nickel, lead and zinc) and organic contaminants (polycyclic aromatic hydrocarbons, polychlorinated biphenyls and a pesticide: dichloro diphenyl trichloroethane). Organisms were surveyed for contaminant bioaccumulation and induction of two hepatic biochemical biomarkers: metallothionein (MT) and cytochrome P450 (CYP1A), as potential indicators of exposure to metallic and organic contaminants, respectively. Using an integrative approach it was established that, although bioaccumulation is in general accordance with sediment contamination, lethality and biomarker responses are not linearly dependent of the cumulative concentrations of sediment contaminants but rather of their bioavailability and synergistic effects in organisms. It is concluded that metals and organic contaminants modulate both MT and CYP1A induction and it is suggested that reactive oxygen species may be the link between responses and effects of toxicity.|
|Versão do Editor:||DOI 10.1007/s10646-009-0373-7|
|Aparece nas colecções:||Ambiente e Sustentabilidade - Artigos em revistas internacionais / Papers in international journals|
Ciências e Tecnologia - Artigos em revistas internacionais / Papers in international journals
Todos os registos no repositório estão protegidos por leis de copyright, com todos os direitos reservados.